Appretude is an HIV-1 integrase strand transfer inhibitor indicated in at-risk persons for Pre-
Exposure Prophylaxis “PrEP” to reduce the risk of sexually acquired HIV-1 infection. Individuals must have a negative HIV-1 test prior to initiating APRETUDE.
After 2 initial injections given 1 month apart, APRETUDE is given as few as 6 times a year.
ZERO daily pills.
Number of yearly treatments: 8
APRETUDE may cause serious side effects including:
Allergic reactions. Call your healthcare provider right away if you develop a rash with APRETUDE. Stop receiving APRETUDE and get medical help right away if you develop a rash with any of the following signs or symptoms: fever, generally ill feeling, tiredness, muscle or joint aches, trouble breathing, blisters or sores in mouth, blisters, redness or swelling of the eyes, swelling of the mouth, face, lips, or tongue
Liver problems. Liver problems have happened in people with or without a history of liver problems or other risk factors. Your healthcare provider may do blood tests to check your liver function.
Call your healthcare provider right away if you develop any of the following signs or symptoms of liver problems: your skin or the white part of your eyes turns yellow (jaundice), dark or “tea-colored” urine, light-colored stools (bowel movements), nausea or vomiting, loss of appetite, pain, aching, or tenderness on the right side of your stomach area, itching, Depression or mood changes.
Call your healthcare provider or get medical help right away if you have any of the following symptoms:, feeling sad or hopeless, feeling anxious or restless, have thoughts of hurting yourself (suicide) or have tried to hurt yourself
The most common side effects of APRETUDE include:
pain, tenderness, hardened mass or lump, swelling, bruising, redness, itching, warmth, loss of sensation at the injection site, abscess, and discoloration, diarrhea, headache, fever, tiredness, sleep problems, nausea, dizziness, passing gas, stomach pain, vomiting, muscle pain, rash, loss of appetite, drowsiness, back pain, upper respiratory infection
These are not all the possible side effects of APRETUDE.
Call your doctor for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088. Please read the Patient Information for APRETUDE and discuss it with your healthcare provider.
For a full list of potential side effects, please see the Apretude website.
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